DSIP

DSIP

    $29.99

    A 9-amino acid peptide that modulates delta-wave sleep architecture and circadian rhythm signaling, studied for sleep onset mechanisms in research models. Premium Research Peptide.

    1000 in stock

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    SKU: am-1785210815892-10 Category:

      Frequently Researched Together

      Sleep & circadian research compounds

      Molecular Profile

      What Is DSIP?

      Naturally occurring nonapeptide first isolated from rabbit brain in 1977

      NonapeptideEndogenousTypeSynthetic nonapeptideCAS Number62568-57-4Molecular FormulaC35H48N10O15Molecular Weight848.8 g/molAmino Acids9 residuesSequenceTrp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-GluPubChem Database

      Storage Requirements

      Stability Information

      Handle with care to maintain potency

      Light sensitiveTemperature sensitive❄️Lyophilized (powder)-20°C•protect from light Reconstituted2-8°C Stability15 minutes (plasma half-life)

      Research Status

      Development History

      First isolated from rabbit brain in 1977 by Schoenenberger & Monnier

      Discovery1977, SwitzerlandDiscoverersSchoenenberger & MonnierOriginRabbit mesodiencephalic ventricleINN NameEmideltideHuman Studies1980s-presentRegulatory StatusResearch compoundOriginal discovery

      European Journal of Anaesthesiology

      Delta sleep-inducing peptide

      2001

      Pollard BJ, Pomfrett CJD

      View SourceInternational Journal of Clinical Pharmacology, Therapy, and Toxicology

      Acute and delayed effects of DSIP on human sleep behavior

      1981•PMID: 6895513

      Schneider-Helmert D, et al.

      View SourceNeuropsychobiology

      Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients

      1992•DOI: 10.1159/000118919•PMID: 1299794

      Bes F, Hofman W, Schuur J, Van Boxtel C

      View SourceEuropean Neurology

      DSIP in the treatment of withdrawal syndromes from alcohol and opiates

      1984•DOI: 10.1159/000115715•PMID: 6548969

      Dick P, Costa C, Fayolle K, et al.

      View SourceEuropean Neurology

      Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes

      1984•DOI: 10.1159/000115716•PMID: 6548970

      Larbig W, Gerber WD, Kluck M, Schoenenberger GA

      View SourceNeuropsychobiology

      Effects of DSIP in man: Multifunctional psychophysiological properties besides induction of natural sleep

      1983•PMID: 6689058

      Schneider-Helmert D, Schoenenberger GA

      View SourceInternational Journal of Neuroscience

      DSIP—a tool for investigating the sleep onset mechanism: a review

      1988•DOI: 10.3109/00207458808990695•PMID: 3286557

      Yehuda S, Carasso RL

      View SourceMolecules

      Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke

      2021•DOI: 10.3390/molecules26175173•PMID: 34500605

      Tukhovskaya EA, et al.

      View SourcePubChem Database

      Delta Sleep-Inducing Peptide

      View Source